Mekedlawit Efrem Successfully Defends Her Thesis on Protein-Ligand Binding and Partition Coefficients

We are thrilled to announce that Mekedlawit Efrem has successfully defended her thesis, marking a significant milestone in her academic journey. Her research focused on evaluating partition coefficients and protein-ligand binding using advanced molecular dynamics simulations.

Mekedlawit's work involved investigating ligand binding to KCNQ3 channels, a critical aspect of understanding ion channel functionality and drug development. She also studied the partition coefficients of fluorescent dyes such as DAPI and ethidium bromide, using cutting-edge enhanced sampling techniques, including metadynamics and umbrella sampling.

Her findings contribute to the growing body of knowledge on molecular mechanisms underpinning protein-ligand interactions and their applications in biophysics and pharmacology.

We extend our heartfelt congratulations to Mekedlawit for her dedication and achievements, wishing her continued success in her future endeavors!