We're interested in sources of biological variation (genetics, development, environment) and the role of morphological variation in primate evolution, as well as applications to human health.
Research
Primate Evolution
Evolution by natural selection is only possible in traits with heritable variation in a population. Much of Dr. Hardin's research has used quantitative methods to estimate the genetic heritability of tooth dimensions in primates to improve our understanding of dental evolution. We are now working on projects to understand how these patterns of heritability vary across closely related species and how they might be influenced by changes in body size and facial structure.
Growth and Development
As organisms grow from infancy to adulthood, the shape of the skull changes to accommodate the changing brain, sensory organs, jaws, and teeth. With collaborators at several institutions, Dr. Hardin has studied growth trajectories of humans with different types of malocclusions to understand key periods for clinical intervention. We are now working on understanding growth in the paranasal sinuses, nasal septum, and airway in humans.
Anatomical Variation
We often find structures in the Anatomy Lab that don't resemble the textbook, and it can be helpful to observe and publish these variants to benefit anatomists and clinicians. Dr. Hardin has worked with students to describe variation in pelvic organs and perineal innervation following gender-affirming surgery. We are currently working on projects looking at vertebral artery pathways and digastric muscle variation.
Laboratory Collaborations
Current collaborators include: Dr. Edie Sperling and Dr. Irisa Arney, COMP-NW, Dr. Heesoo Oh, University of the Pacific Arthur A. Dugoni School of Dentistry, Dr. Rich Sherwood and Dr. Kevin Middleton, University of Missouri